How should a nurse respond when administering an intravenous medication to a patient unfamiliar with such treatment?

When administering an intravenous medication to a patient unfamiliar with this type of treatment, it is important for the nurse to explain that using an oral medication might result in the patient vomiting. This explanation helps the patient understand why the intravenous route is being used and why it may be more appropriate in this situation. By providing this information, the nurse can help the patient feel more comfortable and informed about the treatment they are receiving.

Options B, C, and D do not specifically address the patient's unfamiliarity with intravenous medication and do not provide appropriate information that would help the patient understand the rationale for using this type of administration.